What is REGULATION T? What does REGULATION T mean? REGULATION T meaning - REGULATION T definition - REGULATION T explanation. SUBSCRIBE to our Google Earth flights channel - https://www.youtube.com/channel/UC6UuCPh7GrXznZi0Hz2YQnQ Source: Wikipedia.org article, adapted under https://creativecommons.org/licenses/by-sa/3.0/ license. Federal Reserve Board Regulation T (also referred to as Reg T) is 12 CFR §220 – Code of Federal Regulations, Title 12, Chapter II, Subchapter A, Part 220 (Credit by Brokers and Dealers). Regulation T governs the extension of credit by securities brokers and dealers in the United States. Its best-known function is the control of margin requirements for stocks bought on margin. The initial margin requirement for such margin stock purchases is 50%, and has been since 1974, but Regulation T gives the Federal Reserve the authority to change that percentage. Raising the margin requirement ostensibly reduces risk in the financial system by reducing the potential leverage and total buying power of investors. Conversely, lowering the margin requirement ostensibly increases systemic risk by expanding the buying power and leverage available to investors. Since 1974 the Federal Reserve has not deemed it necessary to adjust the margin requirement, despite periodic extremes of price volatility in the equities markets.
Views: 521 The Audiopedia
More information: https://easa.europa.eu/easadroneproposal Agenda: 9:30 - 9:45 Welcome Trevor Woods, Certification Director, EASA 9:45 - 10:10 Background of the NPA: presentation EC Koen De Vos, Senior Drone Expert, European Commission DG Move; Alessandro Cannizzaro, Impact Assessment Officer, EASA 10:10 - 10:30 Link with the U-Space: presentation SJU Mara Dame, Regulatory Affairs Expert, SESAR 10:30 - 11:00 Structure of the regulation; Boundaries of the open, specific, and certified category; Applicability Yves Morier, Principal Advisor to the Flight Standards Director, EASA
Views: 4247 EASA
The European Parliament did not veto a regulation allowing carmakers to largely exceed emission levels for diesel vehicles in exchange for setting-up of new tests in real driving conditions. Get all the details, soundbites as well as the full audio recordings of the debate at http://euranetplus-inside.eu/eu-lawmakers-back-carmakers-friendly-regulation/ Interviewees and featured guests: - MEP Bas Eickhout - MEP Krišjānis Kariņš Moderator: - Laeticia Markakis, Euranet Plus News Agency ------------------------------- Get more videos of our "U Talking to Me?" series at https://www.youtube.com/playlist?list... Subscribe to our channel at http://www.youtube.com/user/EuranetPlus -------------------------------
Views: 190 Euranet Plus - Official
So finally laws, rules and regulation to fly drones are finally here in India. Here are my quick bits for your information. Effective From 1st Dec 2018. New website will be launched DIGITAL SKY. The government has designed the rules according to the size of the drone being flown. Classification Size Nano less than 250gm Micro 250gm to 2kg Mini 2kg to 25kg Small 25kg to 150kg Large greater than 150kg FEES: UIN (Unique Identification Number)- 1,000 UAOP (Unmanned Aircraft Operators Permit) - 25,000 (5yrs) Renew- 10,000 UIN is required for all category except Nano. Max hight 50ft UAOP is required for all category except Nano and Micro. Max hight 200ft. Leave your doubts below and don't forget to leave any suggestion as well. ----------------------------------------------------------------------------------------- Like on FB- www.facebook.com/regalridermaddie VISIT- www.regalrider.com ----------------------------------------------------------------------------------------- Subscribe Subscribe Subscribe --------------------------------------------------- ---------------------------------- Gadgets Used by me: ---------------------------------- 1. Xiaomi Action Camera - http://amzn.to/2w9amT4 2. Nikon D3300 - http://amzn.to/2jOFqWE 3. DJI Spark Drone - https://www.gearbest.com/rc-quadcopters/pp_637651.html?lkid=11428384 4. Tripod - http://amzn.to/2hlzlfH 5. Head Mount - http://amzn.to/2fdYmZw 6. Chest Mount - http://amzn.to/2hlfE7H 7. Mini Tripod - http://amzn.to/2yg0fwh 8. Power Bank - http://amzn.to/2fe8bXn 9. Boya Mic - https://amzn.to/2Kdr8YV
Views: 467 Regal Rider
Are you ready for the new Market Abuse Regulation (MAR)? Watch this on-demand webinar to learn more about the objectives of the new regulation, the key changes it will bring, how these changes will impact your firm and the steps to take ahead of 3 July 2016. Presenter: Andrew Tuson, Partner, BLP What you will learn: • Extension of the scope of the market abuse regime. • Meaning of inside information and market manipulation under the new regime. • New requirements to notify suspected market abuse. • New requirements on market soundings. • New requirements on managers' transactions. We can help your firm comply with its new obligations under MAR. If you have any questions or concerns, please email [email protected]
Views: 1932 Bryan Cave Leighton Paisner
https://www.ibiology.org/human-disease/cell-cycle-regulation/ Helen Piwnica-Worms provides a historical perspective on cell cycle regulation and outlines important experiments that revealed crucial mediators of the cell cycle. Part 1: Frogs, Clams, Yeast & Human Cancer: Historical Perspective on Cell Cycle Regulation: Helen Piwnica-Worms provides a historical perspective on cell cycle regulation and outlines important experiments that revealed crucial mediators of the cell cycle. Part 2: Translating Fundamental Cell Cycle Principles to Targeted Cancer Therapies: Helen Piwnica-Worms explains how scientists have used their understanding of the cell cycle regulation to generate targeted cancer therapies. Talk Overview: In her first talk, Dr. Helen Piwnica-Worms provides a historical perspective on cell cycle regulation and outlines important experiments in frogs, clams, and yeast that revealed crucial mediators of the cell cycle. Scientists observed that there were factors that allowed cell cycle progression, while there were other factors that prevented the cell from going backward. Using these model organisms, scientists were able to characterize the activation of the inducer of mitosis, the M-Phase promoting factor, which is a heterodimer between cyclin-dependent kinase (Cdc2/Cdk1) and cyclin B. In her second talk, Piwnica-Worms explains how scientists have used their understanding of the cell cycle regulation to generate targeted cancer therapies. The cell has proteins that serve as cell cycle checkpoints, which allows the cell to respond appropriately to DNA damage. Although not all of the checkpoints are functional in a cancer cell, these cells still need the checkpoint proteins to respond to DNA damage. Piwnica-Worms’ laboratory studies the use of combining DNA damage agents with checkpoint inhibitors to selectively kill cancer cells. Her laboratory developed a patient-derived xenograft mouse model to study Triple Negative Breast Cancer (TNBC), and predict how the genotype of the tumor affects treatment. Speaker Biography: Dr. Helen Piwnica-Worms is professor of experimental radiation oncology at the University of Texas MD Anderson Cancer Center. She completed her bachelor’s degree in Biology at St. Olaf College in 1979, a doctoral degree in microbiology and immunology at Duke University Medical School in 1984, and a postdoctoral fellowship in pathology at the Dana-Farber Cancer Institute in 1988. In 1989, Piwnica-Worms joined the faculty of Tufts University Medical School, and in 1992 she moved to the Microbiology and Molecular Genetics department at Harvard Medical School. In 1994, she joined the faculty at Washington University School of Medicine in St. Louis, where she was the chair of Cell Biology and Physiology. Since 2013, Piwnica-Worms assumed the role of Vice Provost of Science and Professor of Experimental Radiation Oncology at the University of Texas MD Anderson Cancer Center. As a basic research scientist, she was interested in understanding how the cell cycle was regulated. She showed how basic research discoveries allow for a better understanding of molecular underpinnings that opens new strategies to treat diseases, like cancer. Using immunocompromised mice, her laboratory developed a mouse model to perform preclinical studies using breast cancer cells from patients. For her scientific contributions, she was an Investigator of the Howard Hughes Medical Institute from 1994 to 2011 and was elected as a member of the National Academy of Medicine in 2013. Learn more about Piwnica-Worms’ research at her lab website: https://www.mdanderson.org/research/departments-labs-institutes/labs/helen-piwnica-worms-laboratory.html
Views: 4077 iBiology
Information to Consumers – Focus on Labeling Regulation EU Nº 1169 2011 on the provision of food information to consumers 23 May 2017 EU FooD-STA Webinar Presenter: Ana Oliveira, Frulact Portugal Moderator: Julian Drausinger, LVA Austria
Views: 105 ISEKI Food
https://www.ibiology.org/cell-biology/reversible-protein-phosphorylation-regulatory-mechanism/ Talk Overview: Edmond Fischer tells an engaging story of how he and Edwin Krebs were the first to observe reversible protein phosphorylation, a mechanism so ubiquitous, it influences almost every cellular process. This Nobel prize winning discovery happened over 60 years ago when Fischer and Krebs collaborated to study how the enzyme glycogen phosphorylase gets activated in cells. Working side-by-side at the bench, they isolated the phosphorylase from the muscle tissue of rabbits, and, in subsequent experiments, revealed that the enzyme was activated by the transfer of phosphate groups from adenosine triphosphate (ATP) to the protein itself. Speaker Bio: Edmond Fischer is Emeritus Professor of Biochemistry at the University of Washington. He, along with his colleague Edwin Krebs, demonstrated for the first time the mechanism of reversible protein phosphorylation on the enzyme glycogen phosphorylase. Fischer and Krebs were awarded the Nobel Prize in Physiology or Medicine in 1992 for this discovery. Since their initial observations, Fischer devoted his research to understanding how reversible protein phosphorylation, particularly tyrosine phosphorylation, plays a role in a variety of cellular processes.
Views: 6799 iBiology Science Stories
Thanks for Watching...!!! Like,comment & share Don't forget to SUBSCRIBE...!!!
Views: 63 Fun Zone
https://www.ibiology.org/genetics-and-gene-regulation/alternative-splicing/ Illustrated overview of the differences between the prokaryotic and eukaryotic transcription process.
Views: 18092 iBiology Techniques
Ultimate Gaming Founder Tom Breitling discusses his new video blog series, that will take us through year one of the regulated, real money, online gaming market through the eyes of one of its pioneers. A lil' birdy said you should Follow us on Twitter at http://www.twitter.com/UltimatePoker We could always use more friends. Like us on Facebook at http://www.facebook.com/UltimatePoker Are you pic happy? Us too. Follow us on http://www.instagram.com/UltimatePoker http://ultimatepoker.com http://ucasino.com http://www.ultimategaming.com
Views: 3567 U
Table of Contents: 00:00 L3.1: Circuits: Introduction to Transcription Networks 00:13 In this lecture … 00:45 "Cognitive Problem" of the Cell 02:44 Transcription Network 03:22 Information Processing 04:28 Transcription Factors 05:16 Transcription Factors 06:13 simplest view of transcription 07:01 Transcription factors as activators 07:41 Transcription factors as repressor 08:14 Gene Expression in Prokaryotes Vs. Eukaryotes 09:03 Gene Expression in Prokaryotes Vs. Eukaryotes 10:18 E. coli Transcription Network 12:08 RegulonDB 12:58 Curated TF – Gene Network in E. coli K12 in RegulonDB 14:31 For Further Knowledge 15:01 Coming Up This video is part of the nanoHUB-U course "Biological Engineering: Cellular Design Principles" currently offered on nanoHUB-U (https://nanohub.org/courses/biod) or on EdX (https://www.edx.org/course/biological-engineering-cellular-design-purduex-nano545x) Cellular Design Principles is a five week course that explores the design principles underlying mechanisms of cellular and biomolecular functions such as cell architecture, energy storage and conversion, sensing and signaling, communication, time keeping, molecular synthesis, memory, and motility. Emphasis will be placed on the chemical, physical, and mathematical features that determine the performance of the biological device. Topics cover both cellular/biochemical processes and molecular/genetic circuits. Examples are presented from reverse engineering of natural systems and design of new synthetic systems.
Views: 876 nanohubtechtalks
What role does activation play in sport performance? Why would we want to learn how to regulate arousal? This video explores two theories about arousal and performance: the Inverted-U hypothesis and the Zone of Optimal Function hypothesis, both of which suggest that having an ability to change your own activation has the potential to improve performance. Click here for the full playlist on Mental Toughness, Psychological Skills Training and Arousal Regulation: https://www.youtube.com/playlist?list=PLvSeo4-B-agX5hI9mHj5xWZ5OQmtJhL_b Michael Noetel Australian Sport Psychologist and Lecturer Any questions or comments? Leave a comment below, message me on twitter @mnoetel or contact me at noetel.com.au
Views: 11305 Mike Noetel Australian Sport Psychologist
In today's video I explain 'The Window of Tolerance' a simple tool to help us emotionally regulate. It's a tool that can be used with anyone of any age either as a general wellbeing tool, or to help regulate more turbulent emotions / behaviours / feelings - e.g. anxiety / anger. I explain the basic premise as well as considering how we can adapt simple strategies to try and keep our emotions within the optimal zone so that we are able to manage the ups and downs that come with day to day life. I hope you find this video helpful. Please take a moment to leave a comment about what you did and didn't like or sharing your own ideas or experiences. Please also to let me know what other topics you'd like me to tackle in future videos and subscribe to be kept up to date with new videos as they’re published. You can also follow me on Twitter: http://www.twitter.com/pookyh Instagram: http://www.instagram.com/pookyh Facebook: http://www.facebook.com/pookyh LinkedIn: http://www.linkedin.com/in/pooky/
Views: 4681 Pooky Knightsmith Mental Health
2nd Annual Spargos Thanksgiving Tournament Losers Bracket Finals featuring 2 Kids From Hampstead (Durkee and Randy) vs Shuck U (Joey P and Jeff Gillen). Regulation and OT1.
Views: 58 Cory Ditzel
In this video, NAR Commercial Regulatory Policy Representative Stephanie Spear discusses the impact of government regulation on the commercial lending environment.
Views: 235 National Association of REALTORS
http://DrPompa.com Toxins effect on hormones and weight loss are epidemic. This is why so many can't lose weight today. Proper detoxification is the only answer for weight loss in America. Regulating hormones like leptin and hormone health and production are the key to weight loss and other chronic conditions like diabetes. True detoxification not only can correct weight loss resistance it has supported the recovery from other conditions such as autism, allergies, asthma, diabetes, chronic fatigue, cancer, heart disease, fibromyalgia, hormone problems, skin conditions and other autoimmune conditions. Dr. Pompa located in Wexford, PA (near Cranberry and Pittsburgh) treats patients and trains doctors from all over the country in his weight loss and detoxification protocols. Visit our web site at www.pompahealthsolutions.com or call our Wexford office to make and appointment at 724-940-7733.
Views: 15499 Dr. Daniel Pompa
The current European Commission put “better regulation” on its agenda. This was “a good idea”, said member of the European Parliament (MEP) Karl-Heinz Florenz in our weekly "U Talking to Me" debate. He blamed Commission vice-president Frans Timmermans, though, for not following up on the idea properly. According to Florenz, the withdrawal of the new rules on waste management, for instance, would be the wrong understanding of improving regulation. MEP Margret Auken (Greens) agreed. She is convinced that the Commission is in the hands of industry lobbyists. Read and listen to our whole audio article with soundbites and the complete audio recording at http://euranetplus-inside.eu/better-regulation-junckers-team-acting-industry-friendly/
Views: 187 Euranet Plus - Official
https://www.ibiology.org/genetics-and-gene-regulation/eukaryotic-mrna/ Part 1 The control of mRNA production and function is a key aspect of the regulation of gene expression. In the first part of this lecture, I will discuss how in eukaryotic cells, the control of mRNA localization, translation and degradation in the cytoplasm allow for the proper regulation of the amount, duration, and location of protein production. The basic mechanisms of these processes are understood and reveal that the mechanisms of localization, translation, and degradation are interconnected. The unique properties of each mRNA are dictated by its intrinsic interactions with cellular machines, as well as its complement of mRNA specific RNA binding proteins and miRNAs. Strikingly, mRNPs are dynamic and can be modulated by protein modifications as well as by modification of the mRNA itself, thereby providing a diversity of targets for the regulation of mRNA function in response to extracellular signals. In 2012, Roy Parker joined the University of Colorado, Boulder after many years at the University of Arizona.
Views: 21458 iBiology
Cerberus Gaming League hosted their very first Monthly Smash Bros Wii U tournament, which boasted a $250 Pot Bonus and massive prize pool. We were joined by WtF Trevonte, Legit, Soulimar, and more more talented Smash Wii U players from Nor Cal! Enjoy the matches and check the comments for time stamps of the matches! Brackets: challonge.com/theregulation
Views: 186 Doc Money
Congratulations ft. Quavo (Official Video) Taken from the album Stoney Song available here: https://PostMalone.lnk.to/StoneyStandardYD Best of Post Malone https://goo.gl/PNSRXq Subscribe for more https://goo.gl/6a7snu Connect with Post Malone: https://www.facebook.com/postmalone https://twitter.com/postmalone https://instagram.com/postmalone https://soundcloud.com/postmalone http://www.postmalone.com Directed by James DeFina Produced by James DeFina & Chris Velona For Definate Films Music video by Post Malone performing Congratulations ft. Quavo. © 2017 Republic Records, a division of UMG Recordings, Inc. http://vevo.ly/UcqTZz Best of Post Malone: https://goo.gl/PNSRXq Subscribe here: https://goo.gl/6a7snu
Views: 1038249569 PostMaloneVEVO
https://www.ibiology.org/genetics-and-gene-regulation/epigenetics/ In the first of his videos, Dr. Allis introduces the concept of epigenetics; a change in a cellular phenotype that is not due to DNA mutation but due to chemical modifications of proteins that result in changes in gene activation. In the nucleus, DNA is wrapped around proteins called histones to form chromatin. How tightly the chromatin is packaged determines whether genes are active or not. This switch between the “on and off” state of chromatin is regulated by chemical modification of histones. Allis describes work from his lab and others that identified the enzymes that add, remove and recognize the histone modifications. Changes in histone modification can cause a number of diseases including cancer. A key difference between genetic mutations and epigenetic modifications is that epigenetic changes are reversible making them an attractive drug target. Dr. Allis focuses on the role of epigenetics in development and disease in his second talk. Histones can be modified on a number of amino acids, particularly lysines, by the addition of acetyl or methyl groups. Combinatorial patterns of these modifications act to enhance or repress gene expression. Allis describes work from his lab and others, which demonstrates that mutations in histone (for instance a lysine to methionine mutation) may block these modifications and, thus, impact gene expression. Sadly, these “onco-histone” mutations have been identified as the cause of many diseases including pediatric brain tumors and pancreatic neuroendocrine tumors. Speaker Biography: C. David Allis is the Joy and Jack Fishman Professor and Head of the Laboratory of Chromatin Biology and Epigenetics at The Rockefeller University. Allis’ lab studies how modifications to histones, the proteins that package DNA, influence gene expression and the implications these changes have for human disease. Allis has been honored with many awards for his pioneering research including the 2015 Breakthrough Prize in Life Sciences, the 2014 Japan Prize, the 2007 Canada Gairdner International Award and many others. Allis is a member of the National Academy of Sciences USA, the American Academy of Arts and Sciences and the French Academy of Sciences. Allis received his BS in biology from the University of Cincinnati and his PhD in biology from Indiana University and he was a post-doctoral fellow at the University of Rochester.
Views: 21997 iBiology
https://www.ibiology.org/genetics-and-gene-regulation/alternative-splicing/ In the first part of her talk, Dr. Moore explains that eukaryotic pre-mRNA contains long stretches of non-protein coding sequences interspersed with protein coding regions. By recognizing specific sequences, cellular machinery splices out the non-coding introns leaving just the protein-coding exons in mRNA. Although at first glance this may seem like a wasteful process, it is splicing that facilitates the evolution of new genes, and alternative splicing that allows a limited number of genes to produce a large number of proteins.
Views: 22851 iBiology
https://www.ibiology.org/genetics-and-gene-regulation/alternative-splicing/ Overview of the different types of alternative splicing and their proteomic consequences.
Views: 14108 iBiology Techniques
https://www.ibiology.org/neuroscience/sodium-channels/#part-3 Lecture Overview: How does a baseball player react quickly enough to hit a 90 mph fastball or a tennis player to hit a 60 mph serve? All of the fast events in our bodies, such as vision, hearing, nerve conduction and muscle contraction, involve electrical signals. In Part 1 of his talk, Dr. Catterall explains how the flow of sodium and potassium ions, through specific channels in the cell membrane, creates an electrical signal in nerve and muscle cells. He describes the structure and function of the sodium channel and its important role in physiology and pharmacology. In Part 2 of his talk, Catterall describes how voltage gated sodium channels function at an atomic level. Bacterial Na+ channels in the NaChBac family contain many of the elements of mammalian Na+ channels but in a much simpler form. Using X-ray crystallography to study NaChBac proteins, Catterall and his colleagues determined which domains of sodium channels are responsible for sensing voltage differences across the cell membrane and how these domains trigger the opening of the channel pore. It was also possible to identify the structural changes leading to the slow inactivation of channels after multiple rounds of opening and closing and to understand how NaChBac establishes its specificity for Na+ ions. In his third talk, Catterall switches his focus to voltage gated calcium channels. Na+ and Ca2+ channels share a common ancestor and consequently, much of the overall structure of the voltage sensing domain and the central pore is conserved. In spite of this homology, the calcium channel selects specifically for Ca2+ ions, even in the presence of an excess of Na+. Upon entry into the cell, Ca2+ ions regulate numerous intracellular processes. Catterall explains how his group was able to engineer a bacterial calcium channel that allowed them to identify the residues required for Ca2+ selectivity. He also describes experiments demonstrating that Ca2+ ions act locally within the cell, allowing for targeted regulation of cellular functions such as learning and memory in the brain and contraction in skeletal and cardiac muscle. Speaker Bio: Bill Catterall is Professor and Chair of the Department of Pharmacology at the University of Washington where he has been a faculty member since 1977. Catterall received his BA in Chemistry from Brown University and his PhD in Physiological Chemistry from Johns Hopkins University. He was a post-doctoral fellow with Dr. Marshall Nirenberg and a staff scientist at the NIH for a few years before moving to the University of Washington. Catterall and his colleagues discovered the voltage-gated sodium and calcium channels responsible for generating the electrical impulses necessary for most physiological functions. His lab continues to study the structure and function of these channels, their physiological regulation, and their interaction with medically important drugs. Catterall is also interested in understanding how impaired channel function may lead to human disease. Catterall has been recognized with numerous awards and honors for his contributions to the fields of electrophysiology, pharmacology, neuroscience, and cell biology. These include receiving The Bristol-Myers Squibb Award for Distinguished Research in neuroscience in 2003, The Gairdner International Award of Canada in 2010, election to the U.S. National Academy of Sciences in 1989, the Institute of Medicine and the American Academy of Arts and Sciences in 2000, and as a Foreign Member of the Royal Society of London in 2008.
Views: 11564 iBiology
The Better Regulation Center is a specialized analytical unit established within the Slovak Business Agency. Our analytical unit was created following the Initiative of the European Union on the promotion of Small and medium enterprise, also known as the Small Business Act, with the aim to accomplish the objectives stipulated by this Initiative. The Better Regulation Center comprises a team of specialists in the fields of legislation and regulatory impact assessment on the business sector (the so-called Business Impact Assessment), whose mission is the reduction of the disproportionate regulatory burden of businesses and an improvement in the business environment in Slovakia. Website: http://lepsiezakony.sk/
Views: 48 SBA Agentúra
Emergence of Life [U Illinois] PLAYLIST: https://tinyurl.com/EmergenceOfLife Part 5: Paleozoic Plants, Reptiles, and the Transition to Land Lesson 6 - Reptiles Heating Up Thermal Regulation Notes: https://tinyurl.com/EmergenceOfLifeNotes
Views: 8 Bob Trenwith
Regulation 6 of CMR 1957 कोल माइन्स रेगुलेशन 1957 रेगुलेशन 6 Notice of abandonment or discontinuance खान बन्द करने या कार्य स्थगित रखने का नोटिस Plz subscribe our channel for further updates जय हिन्द जय भारत भारत माता की जय
Views: 848 Mining Technical
Ban U-Turn? Indian Govt. Panel Suggests Cryptocurrency Regulation: Report Get exclusive fiat and cryptocurrency analysis on Hacked.com for just $39 per month. Click here now!An Indian government panel reportedly tasked to look into cryptocurrency policy isn’t in favor of a sweeping ban akin to the recent banking blockade enforced by the country’s central bank. Citing sour... ► SUBSCRIBE FOR MORE VIDEOS: https://goo.gl/NYaHq2 ► Bitcoin News -Alt Coin news - coin telegraph - coindesk - coin market cap https://goo.gl/45UVFu ★★★ Thanks for watching! Please leave a like if you enjoyed and tell me what you think in the comments! Thanks ★★★
Views: 29 CoinKorea
U Turn on Diesel Price Regulation Follow Rahul Gandhi on YouTube : http://bit.ly/2htLnb7 Facebook: https://www.facebook.com/rahulgandhi/ Twitter: https://twitter.com/OfficeOfRG Instagram: https://www.instagram.com/rahulgandhi/ Follow Indian National Congress Follow the Indian National Congress on Facebook: https://www.facebook.com/IndianNation... Twitter:https://twitter.com/INCIndia Instagram: https://www.instagram.com/incindia/
Views: 35 Indian National Congress
https://www.ibiology.org/genetics-and-gene-regulation/rna-dna-differences/#part-3 Part 1: Individual Variation in Gene Expression: Dr. Vivian Cheung employs a genetic approach to identify regulators that influence expression levels of genes. Part 2: It’s in our RNA: A study of the RNA-DNA differences: Dr. Vivian Cheung overviews a new form of RNA editing that resulted in RNA-DNA differences (RDDs) that couldn’t be explained by previous mechanisms. Part 3: Mechanisms that underlie RNA editing and RNA-DNA differences: Cheung overviews the molecular mechanisms that lead to RNA editing and other forms of RNA-DNA differences (RDDs). Talk Overview: Variations in gene expression generate much of the biodiversity we observe in nature. Dr. Vivian Cheung employs a genetic approach to identify regulators that influence expression levels of genes. By treating gene expression levels as quantitative traits, her laboratory was able to correlate DNA variants with gene expression levels. This analysis revealed cis- and trans-acting gene regulators such as DNA demethylase KDM4C, a master regulator of a subset of genes that control growth and apoptosis. By sequencing and systematically comparing the DNA and RNA of individuals, the Cheung laboratory discovered thousands of sites where the RNA was different from its corresponding DNA sequence. Although other forms of RNA editing have been reported before, this report showed RNA-DNA differences (RDDs) that couldn’t be explained by previous mechanisms. Cheung’s laboratory characterized these RDDs and showed that these changes in the RNA were permanent and could result in a different protein. In her third talk, Cheung overviews the molecular mechanisms that lead to RNA editing and other forms of RDDs. Her laboratory showed that the deaminase ADAR binds to a specific motif of the RNA to mediate A- to G- editing. In the other hand, they showed that RDDs are formed 60-100 nucleotides outside the polymerase bubble, which perfectly time with the formation of R-loops, a hybrid between the template DNA and the nascent RNA during transcription. A mutation that results in an overactive senataxin, a helicase that resolves R-loops, causes a rare form of amyotrophic lateral sclerosis (ALS). Cheung’s group showed that the increased helicase activity that resulted from senataxin mutation correlates with a decrease in R-loops in these patients and therefore a decrease in RDDs. Speaker Biography: Dr. Vivian Cheung is a professor of genetics at the University of Michigan and a Howard Hughes Medical Institute investigator. Cheung obtained a bachelor’s degree in microbiology at the University of California, Los Angeles and graduated from Tufts School of Medicine. She continued her medical training as a pediatric resident at UCLA, and completed a neurology fellowship at The Children’s Hospital of Philadelphia. Her laboratory uses molecular and computational methods to understand the genetic basis of human traits and diseases. Cheung wants to create genetic tools to improve preventive medicine and help better patient care. For her scientific contributions, Cheung was elected member of the National Academy of Medicine (2011), and received the Curt Stern Award in 2010. Learn more about Cheung’s research at her lab website: http://cheunglab.lsi.umich.edu/home/
Views: 2420 iBiology
Roomie’s video: https://www.youtube.com/watch?v=ojvqIumZtnU Dave’s BTS video: https://www.youtube.com/watch?v=3E_1fspZQ4c Stream “Congratulations”: http://smarturl.it/CongratulationsPewds Credits: Music & Lyrics: David Paul Brown Music & Lyrics: Joel Gustaf “Roomie” Berghult Music & Lyrics: Felix Arvid Ulf Kjellberg Filmed & edited by http://youtube.com/JonasTheFrisk?sub_confirmation=1 Mixed by Eric Johansson at http://binadio.com/ Beat production by Apollo V Beat modification & vocal production by Joel Gustaf “Roomie” Berghult -- N E W M E R C H : https://represent.com/pewdiepie 🔥 (◡‿◡✿) Submit M E M E S: https://www.reddit.com/r/PewdiepieSubmissions/ ༼♥ل͜♥༽ __ TSUKI: https://tsuki-co-uk.myshopify.com __ :::::::My Setup:::::::: (Affiliate links) Chair:: ONLY 399 ! USA & Asia: https://usa.clutchchairz.com/product/pewdiepie-edition-throttle-series/ Europe: https://europe.clutchchairz.com/en/product/throttle-series-pewdiepie-edition/ Canada: https://canada.clutchchairz.com/product/throttle-series-pewdiepie-edition/ Elgato green screen: http://e.lga.to/PewDiePie (Affiliate) __ :::::::Check out: ::::::::http://store.steampowered.com/app/703840/Animal_Super_Squad/ (A game I helped make and affiliated with) __ Outro: Animation: https://www.youtube.com/user/jae55555 Song: https://www.youtube.com/channel/UC3e8EMTOn4g6ZSKggHTnNng
Views: 109922435 PewDiePie
Cerberus Gaming League's second monthly event, The Regulation 2. Featuring a lot of top talent from Nor Cal's Smash Bros Wii U community, a $150 pot bonus, and a great deal of hype matches! All the matches here will be timestamped. Will the be doubles at the Regulation 3? Probably not.
Views: 64 Doc Money
The Food and Drug Administration has announced a new series of regulations to control e-cigarettes and cigars. Other tobacco products will also be affected by these new rulings. The FDA already regulated cigarettes, bulk and smokeless tobacco. The new announcement extends their power to control electronic cigarettes, hookahs and all pipe tobacco. Under the new regulations, purchasers of any of these products will need to be at least 18 years old. Some states may establish higher age limits. The agency will also need to approve any advertising claiming reduced risk from tobacco use. Free samples from tobacco manufacturers and distributors would be prohibited, and all companies selling tobacco products will need to register with the FDA. The FDA regulations are subject to a 75-day waiting period, during which the agency will collect feedback from the public. Tobacco sales from vending machines will be prohibited. Packaging for all affected products will be required, warning users of health risks. When new rules go into effect, warnings about addiction wold be the only mandatory labels on e-cigarettes. Vaporizers contain a small amount of nicotine in liquid form. When a user presses a button, the sample is heated until some of the material converts into vapor. These devices have not yet been subject to federal regulation, a situation which FDA commissioner Margaret Hamburg described as "the wild, wild, west." The government official worries that e-cigarettes "might be a gateway to other harmful tobacco products" for young people. According to the Centers for Disease Control, during February, there were 215 calls to poison centers nationwide involving e-cigarettes. Just over 100 of these calls involved minors, Hamburg told the press. There are roughly 80 million people under the age of 19 living in the United States, and 42 million adult smokers. The FDA commissioner stated, "We think that there's a lot of information that needs to be understood about e-cigarettes and their use. We're trying to help provide some of that information through research that we're conducting." http://www.cnn.com/2014/04/24/health/fda-e-cigarette-regulations http://www.msnbc.com/msnbc/fda-e-cigarette-cigar-regulations-roll-out http://www.bustle.com/articles/22217-fda-proposes-e-cigarette-ban-for-minors-plans-to-regulate-other- tobacco http://www.nytimes.com/2014/04/24/health/fda-will-propose-new-regulations-for-e-cigarettes.html? hpw&rref=us http://www.usatoday.com/story/news/nation/2014/04/24/fda-e-cigarette-rules/8050875 Download your free Next News "Heroes & Villains" Poster here: http://nextnewsnetwork.com/the-2013-heroes-villains-posters Donate USD: http://nnn.is/donate-dollars Donate BTC: http://nnn.is/donate-bitcoin LIVE: http://NextNewsNetwork.com Facebook: http://Facebook.com/NextNewsNet Twitter: http://Twitter.com/NextNewsNet Sub: http://NNN.is/the_new_media Meet the Next News Team: http://youtu.be/2QnNKwQ2WkY Hashtag: #N3 About: Next News Network's World News program airs daily at 6pm and 11pm Eastern on Comcast, DirecTV and Over-the-Air and Online at http://NNN.is/on- World News is available to 6 million viewers from South Beach to Sebastian, Florida and to 2 million viewers in Boston, Massachusetts via . broadcasts on RF channel 44 (virtual channel 9) from Palm City and is carried on cable TV channels 44 (SD) and 1044 (HD) by AT&T, on cable channels 17 (SD) and 438 (HD) in West Palm Beach by Comcast, on satellite channel 44 (SD) in West Palm Beach by DIRECTV, and on -Boston which broadcasts on RF channel 38 (virtual channel 6) from the Government Center district in downtown Boston. More about : http://en.wikipedia.org/wiki/ #SR Community Guidelines Disclaimer: The points of view and purpose of this video is not to bully or harass anybody, but rather share that opinion and thoughts with other like-minded individuals curious about the subject to encourage conversation and awareness.
Views: 3892 The Next News Network
https://www.ibiology.org/genetics-and-gene-regulation/eukaryotic-mrna/#part-2 In the second part of this lecture, I will provide an overview of why the regulation of translation and mRNA degradation is an important aspect of the control of gene expression in eukaryotic cells. In addition to the translating pool of mRNAs associated with polysomes, recent experiments have identified P-bodies and stress granules as specific cytoplasmic compartments wherein untranslated mRNAs accumulate. In addition to mRNAs, P-bodies tend to contain translation repressors and mRNA degradative enzymes, while stress granules reflect mRNAs in association with some translation initiation factors and RNA binding proteins. P-bodies and stress granules interact and suggest a dynamic process wherein eukaryotic mRNAs remodel their interacting proteins and enter and exit translation, thereby affecting the control of mRNAs in the cytoplasm. We are interested in defining the mechanisms by which P-bodies and stress granules assemble and how cells regulate the movement of mRNAs between these different biochemical and cell biological compartments. Several approaches will be described including biochemical and genetic analyses of known proteins modulating these events, as well as the identification of new factors affecting P-body and stress granule formation and function. In 2012, Roy Parker joined the University of Colorado, Boulder after many years at the University of Arizona.
Views: 11980 iBiology
Ban U-Turn? India’s Central Bank Admits Cryptocurrency Regulation is Necessary In a first, India’s central bank has called for the regulation of the domestic cryptocurrency sector during Friday’s hearing at the Supreme Court, weeks after enforcing a banking ban against crypto companies. Earlier in April, the Reserve Bank of India (RBI) issued a circular that forbade all financ... ► SUBSCRIBE FOR MORE VIDEOS: https://goo.gl/NYaHq2 ► Bitcoin News -Alt Coin news - coin telegraph - coindesk - coin market cap https://goo.gl/45UVFu ★★★ Thanks for watching! Please leave a like if you enjoyed and tell me what you think in the comments! Thanks ★★★
Views: 12 CoinKorea
Rand Paul: "I'm still learning about it. It's 20,000 pages of regulations. The Bill was 2,000 pages and I didn't realize this until this week, the whole idea of you losing or getting your insurance cancelled wasn't in the original Obamacare. It was a regulation WRITTEN BY PRESIDENT OBAMA, three months later.So we had a vote, this is before I got up there. The Republicans had a vote to try to cancel that regulation so you COULDN'T BE CANCELLED, to grandfather everybody in. You know what the vote was? Straight party line. EVERY DEMOCRAT VOTED TO KEEP THE RULE THAT CANCELS YOUR INSURANCE." Full Speech: Rand Paul Speaks At The Charleston Meeting - 11/11/2013 https://www.youtube.com/watch?v=22qAbmL0yDw
Views: 254 VisionLiberty